Direct C–C Bond Cleavage of CH3CN as a Single‐Carbon Synthon：Synthesis of Pyrrolo[1,2‐a]quinoxalines via Electrochemical Oxidation

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A direct electrochemical redox reaction involving radical cross‐coupling cyclization for the synthesis of pyrrolo[1,2‐ a ]quinoxaline derivatives from 1‐(2‐aminophenyl)pyrroles and CH 3 CN has been developed, which includes the functionalization of C( sp 3 )−H bonds as well as the construction of C−C and C−N bonds. Notably, the control and deuterium‐labelling experiments suggest that CH 3 CN in this reaction acts as both a carbon source via C−C cleavage and solvent. The reaction features metal‐ and oxidant‐free conditions, and various substituted pyrrolo[1,2‐ a ]quinoxaline derivatives were obtained.