Subcutaneous Panniculitis-like T-cell Lymphoma Mimicking Angioedema: Case Report and Brief Literature Review

Various medical conditions that cause subcutaneous swelling can mimic angioedema, and appropriate differential diagnosis is sometimes challenging for clinicians because of its relative rarity. We herein report a case of a 38-year-old man with primary subcutaneous panniculitis-like T-cell lymphoma that was initially misdiagnosed as angioedema because of the patient's prominent facial swelling. Our experience shows that not all facial edema are angioedema and reinforces the importance of clinical suspicion, appropriate evaluation, and treatment for patients with an atypical presentation of facial swelling.