Análise Do Potencial De Ferrocenilchalconas Contra Vermes Adultos Do Schistosoma Mansoni

Schistosomiasis mansoni is a parasitic disease caused by the trematode Schistosoma mansoni. Currently, the treatment of schistosomiasis is based on the use of just one drug, praziquantel. However, the extensive use of this drug can lead to the selection of tolerant and resistant strains, making it necessary to investigate new chemotherapeutic alternatives. In recent years, chalcones, substances found in various plants and also obtained by synthetic means, have been recognised for their biological activities, including antibacterial, antifungal, antiviral and antiparasitic activities. The aim of this research was to analyse the potential of ferrocenylchalcones against adult S. mansoni worms. The results of this study show that chalcona can be considered a new therapeutic alternative for treating S.mansoni.