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October 8, 2025MedicineOpen Access

Successful treatment of anti-neutrophil cytoplasmic antibody-associated inflammatory pseudotumour with rituximab: A case report

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Authors

LGL. GaoSecond People’s Hospital of YibinHZHua ZhaoNanchang UniversityCLChaoyang LiangChinese Academy of Medical Sciences & Peking Union Medical College

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Overview

Case report illustrates effective treatment of ocular inflammatory pseudotumor with rituximab, indicating superior outcomes over traditional therapies.

Key Points

  • Significant improvement was observed after rituximab therapy, allowing for steroid tapering without relapse.
  • Initial therapy with corticosteroids and cyclophosphamide was ineffective, leading to recurrent symptoms upon steroid reduction.
  • A patient with ANCA-associated vasculitis presented with ocular symptoms and evolved challenges in treatment for the steroid-dependent condition.
  • Rituximab emerges as a promising alternative in cases of refractory ocular symptoms or when serological markers show improvement yet symptoms persist.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1be6950a706b22b5936https://doi.org/10.1097/md.0000000000045044
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1B Lineage Cells in ANCA-Associated Vasculitis2021 · 26 citations
  2. 2Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders2019 · 254 citations
  3. 3Therapy of ocular complications in ANCA+ associated vasculitis2021 · 15 citations
  4. 4Ocular Manifestations of Patients With Circulating Antineutrophil Cytoplasmic Antibodies1990 · 75 citations