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October 8, 2025Renal FailureOpen Access

Accessing the relationship between estimated glucose disposal rate and the incidence of the kidney disease: results from the China Health and Retirement Longitudinal Study

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Authors

XYXiaolan YeWLWentong LiuQTQinglai Tang

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Overview

Analysis reveals lower estimated glucose disposal rate increases kidney disease risks in older adults, suggesting a preventive focus may be beneficial.

Key Points

  • Higher estimated glucose disposal rate significantly reduces the risk of rapid kidney function decline.
  • Logistic regression indicated that each 1.0-SD increment in estimated glucose disposal rate lowered the odds of developing new-onset CKD.
  • Subgroup analyses showed a marked increase in kidney disease risk when estimated glucose disposal rate fell below a threshold of 10.405 mg/kg/min.
  • Predictive models incorporating estimated glucose disposal rate enhanced accuracy in identifying individuals at risk of kidney disease.

Cite This Study

Ye et al. (2025) studied this question.

synapsesocial.com/papers/68e5c1c76950a706b22b5ecehttps://doi.org/10.1080/0886022x.2025.2565408
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Longitudinal changes in estimated glucose disposal rate and risk of cardiovascular disease among adults with cardiovascular–kidney–metabolic syndrome stages 0–3: a nationwide prospective cohort study2025
  2. 2A practical tool for risk stratification: eGDR as a predictor of incident diabetic kidney disease2026
  3. 3Association between changes in estimated glucose disposal rate and composite kidney outcome in middle-aged and elderly individuals: a national cohort study2025
  4. 4Changes in the estimated glucose disposal rate and incident cardiovascular disease in patients with cardiovascular–kidney–metabolic syndrome stages 0–3: a prospective cohort study in China2025 · 2 citations
  5. 5Changes in the estimated glucose disposal rate and incident cardiovascular disease in patients with cardiovascular–kidney–metabolic syndrome stages 0–3: a prospective cohort study in China2025