MR-derived breast density (MagDensity) enables reliable density measures across field strengths and vendors

The current standard of care for breast density assessment using mammography according to the Breast Imaging Reporting and Data System (BI-RADS) is subjective and can also suffer from intra- and inter-reader variability. Quantitative measurement of breast density is crucial for personalized risk assessment and longitudinal monitoring. Our team has previously developed a quantitative, MR-derived BD (MagDensity) measurement based on fat-water decomposition, which has shown high accuracy and test-retest reproducibility within a single scanner. In order for this measure to be practical for clinical adoption, this study aims to determine the reliability of MagDensity across scanners, field strengths, and vendors.