Optimizing Breast Isotropic DCE-MRI Imaging Based on Compressed SENSE Technique

Dynamic contrast-enhanced (DCE) MRI is a multi-phase sequence that is limited by long scan times, which makes acquisition acceleration necessary to accomplish clinical feasibility. The aim of this study was to investigate the effect of different Acceleration Factors (AFs) on the image quality of isotropic DCE-MRI acquired with the Compressed SENSE (CS) technique, and to find the optimal AF for the isotropic DCE-MRI. CS factors of 4 to 7 were compared against the conventional SENSE technique in 43 patients. Preliminary results show a CS factor of 5 is the optimal AF with optimized image and velocity data quality.