Correlation of quantitative synthetic mapping imaging with cervical squamous carcinoma pathology

Clinical and pathological staging are vital for management of Cervical squamous carcinoma (CSC). In this study, using synthetic MR technique, we investigate quantitative T1, T2 and PD measurements in different clinical and pathological stage groups. Performance of those quantitative measurements in diagnosing poorly-differentiated CSC is also investigated. We find T2 values are higher in late clinical stage CSC. Results also show a correlation between quantitative measurements and the degree of pathological differentiation. ROC analysis demonstrate that T1 and T2 values can differentiate poorly-differentiated CSC from intermediate and well differentiated CSC1.