Synthetic MRI derived quantitative mapping in predicting Lymphovascular interstitial infiltration status of cervical cancer

This study aimed to investigate whether synthetic-MRI derived quantitative maps can predict lymphovascular interstitial infiltration (LVSI) status in cervical cancer. 49 patients with cervical cancer were recruited with the status of LVSI confirmed by pathology. Synthetic MRI derived T1, T2 and PD mapping were obtained for each patient. Statistical differences were shown in T1 and PD values between LVSI-positive and LVSI-negative patients. An optimal diagnostic efficacy was further shown for T1+PD with high AUC of 0.777. With these findings, it can be concluded that relaxation maps derived from synthetic MRI may be helpful for predicting LVSI status in cervical cancer.