Synthetic MRI derived Quantitative Maps in Diagnosis of Endometrial Carcinoma

This study aimed to investigate whether synthetic-MRI can diagnose endometrial carcinoma (EC). 116 patients were recruited, including submucous myomas(SM),endometrial hyperplasia and endometrial polyps(EH&EP) and EC. Synthetic MRI derived T1, T2 and proton density(PD) mapping were obtained for each patient. Significantly different T1 and T2 were shown between EC and SM, and the optimal diagnostic efficacy was for T1+T2 with AUC of 0.865. T2 and PD were also different between EC and EH&EP. The corresponding optimal diagnostic efficacy was for T2+PD with AUC of 0.690. With these findings, synthetic-MRI may thus be effective in differentiating EC from other intrauterine diseases.