Retrospective and prospective accelerated T1ρ/T2 mapping with Compressed Sensing: high resolution T1ρ mapping and simultaneous T1ρ/T2 mapping

Quantitative MR T1rho T2 imaging shows promising results on detecting early-stage osteoarthritis, but long scan time limits the spatial resolution, making it vulnerable to partial volume averaging. Such effect reduces the sensitivity to small focal degeneration. In this study, compressed sensing reconstruction with spatio-temporal finite difference regularization was used to accelerate high-resolution (slice thickness < 2mm) T1rho imaging and standard-resolution simultaneous T1rho and T2 imaging, and evaluated the result comparing with reference imaging, retrospective and prospective reconstruction, and scan-rescan repeatability.