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The presented method allows to automatically adjust laser power relying on real-time rapid volumetric MR-thermometry using the proton resonance frequency (PRF) shift technique. The laser output power is regulated every second to force temperature to follow a predefined temperature-time profile using a PID controller, taking MR-temperature data as input. The proposed temperature regulation algorithm is successfully validated in vivo in the skeletal muscle of a pig.
Desclides et al. (Wed,) studied this question.