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Pulmonary perfusion analysis reveals impaired lung perfusion in older hospitalized COVID-19 patients, suggesting severe infection causes lasting cardiopulmonary vascular deficits.
Pulmonary perfusion analysis of cardiac magnetic resonance imaging in patients with previous COVID-19 may help phenotype patients with advanced cardiopulmonary disease. Lung perfusion analysis was performed and results were correlated with clinical data in patients who were treated for COVID-19 at Johns Hopkins institutions. Older age and hospitalization for COVID-19 were found to be related to worse pulmonary perfusion, as measured by the perfusion parameter 50% max intensity, suggesting that one long-term sequela of severe COVID-19 that requires hospitalization, particularly in older patients, is a global bilateral decrease in the speed at which the lungs are perfused.
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Lancaster et al. (2024) studied this question.
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