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In this study, we analyzed pH values obtained via high-resolution 31P MRSI at 7T in different subjects and different regions of the human brain, and identified a trend towards lower pH values in the frontal region compared to other brain regions. The potential regional variation should be taken into account in cases, where only small pH changes between different tissues are expected and partial volume effects might dominate.
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Platek et al. (2024) studied this question.
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