Quantitative T1/T2 relaxometry can be simultaneously generated from Synthetic MRI (SyMRI) in one single scanning and short time. This study aims to use SyMRI to evaluate the brain structural changes in preschool children with autism spectrum disorder (ASD), and the correlation between T1/T2 and ASD scores, as well as the diagnostic efficacy. We found that Synthetic T1 and T2 could be helpful for brain abnormity assessing, pathophysiological mechanism understanding and diagnosis of ASD.
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Li et al. (2024) studied this question.
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