Effects of neuropathic pain on cerebral hemodynamics in spinal nerve ligation model

In this study, the effects of neuropathic pain on cerebral hemodynamics was investigated. For the neuropathic pain model, a spinal nerve ligation model was operated and validated by Von Frey test. To estimate the cerebral hemodynamics, DSC-MRI was performed up to 28 days after surgery. As a result, it is possible to specify when or where the neuropathic pain strongly affects cerebral perfusion.