A Preliminary study of Idiopathic Pulmonary Fibrosis using 3D ventilation map based on 3D Ultrashort Echo time Imaging

Idiopathic pulmonary fibrosis (IPF) is a specific form of idiopathic interstitial pneumonia of unknown cause, the most common and fatal of these interstitial lung diseases. A study on the quantitative assessment of IPF severity based on signal intensity in hyperpolarized MRI lung imaging has recently been proposed. In this preliminary study, it was shown that non-contrast-enhanced 3D ultrashort echo-time (UTE) MRI could diagnose ventilation defects in lesions in patients with IPF using UTE-based 3D ventilation maps and histograms in combination with 3D UTE structural images.