Q-Dixon MRI and High-Speed T2-Corrected Multiecho MR Spectroscopy to Quantify Thigh Muscle Fat Content in Dialysis Patients

This study evaluated the correlation and consistency of proton density fat fraction (PDFF) measured by Q-Dixon magnetic resonance imaging (MRI) and high-speed T2-corrected multiecho (HISTO) magnetic resonance spectroscopy (MRS) for quantifying thigh muscle fat content in patients undergoing dialysis. Q-Dixon MRI exhibited good correlation and consistency with the HISTO MRS for thigh muscle fat quantitative measurements indicating that Q-Dixon MRI may be a reliable alternative to HISTO MRS in clinical assessment and radiological quantitative evaluation of thigh muscle fat infiltration.