The value of 3D APTw Combined Intravoxel Incoherent Motion in Evaluation of the Renal Function in Chronic Kidney Disease

Early diagnosis of chronic kidney disease (CKD) is difficult because of its hidden condition, mild symptoms and imperceptible symptoms. Amide proton transfer weighted (APTw) is a new contrast-free MR imaging technique, which can non-invasively detect the changes of amide proton concentration in endogenous mobile proteins and polypeptides in tissues. Intravoxel income motion (IVIM) can simultaneously obtain the microcirculation perfusion and water molecule diffusion of patients. The results showed that APTw and IVIM parameters APT, D* and D had good diagnostic efficiency in evaluating CKD renal function, especially the cortex APT value.