Noninvasive assessment of the renal function, the Oxford classification and the prognostic risk stratification of IgAN by DWI and BOLD MRI

Purpose To explore whether IVIM-DWI and BOLD-MRI can assess the renal function, Oxford classification and prognostic risk stratification of IgAN patients. Methods This retrospective study included 46 IgAN patients and 20 healthy volunteers for renal MRI examinations. T2* values on BOLD images and ADC, Dt, Dp, fp values on IVIM-DWI images were measured. Results: Cortical Dt generated the largest area under the curve for differentiating 5-year risk scores ≤ 10% from 5-year risk scores > 10%, and for differentiating T0 from T1/T2. Conclusions IVIM-DWI and BOLD-MRI can assess the renal function, Oxford classification, and prognostic risk stratification of IgAN patients.