Feasibility of a multi-site and cross-platform liver 31P MRSI processing pipeline for three 7T clinical MRI vendors

We present preliminary baseline results from three-vendor 7 T MRSI for applications on liver 31P MRS. Liver scans were performed on 21 healthy volunteers, at 4 sites and 3 different 7T MR scanner platforms. Data were analysed using a new Matlab pipeline combining the best methods from our labs. This pipeline is operator independent and we report here the liver metabolites as ratios of PME/PDE and Pi/ATP concentrations. The cross-site average PME/PDE was 0.63 ± 0.12, and the cross-site average Pi/ATP was 0.76 ± 0.11. This compares favourably with literature reports [Purvis et. al., 2017].