Peri-tumoural lipid composition plays a major role in the disease progression of breast cancer, and novel chemical shift-encoded imaging (CSEI) allows rapid lipid mapping of the whole breast. We have previously observed an imbalance of peri-tumoural lipid composition in postmenopausal women with breast cancer using CSEI. Monitoring of lipid composition for early sign of tumour regression might be crucial for an accurate differentiation of patients responding to neoadjuvant chemotherapy (NACT). We hence set out to elucidate the longitudinal change in lipid composition in the peri-tumoural region and the whole breast in patients with breast cancer using CSEI.
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Cheung et al. (2024) studied this question.
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