MRI-based tumor shrinkage patterns after early neoadjuvant therapy in breast cancer: Correlation with subtypes and pathological response

We analyzed the correlation between MRI-based tumor shrinkage patterns after the early stage (first and second cycles) of NAC and pathological response in different subtypes. Fragmentation and diffuse decrease are collectively referred to as non-CS. We found that non-CS could be observed in some patients after the early stage of NAC, and non-CS and pCR were significantly correlated in HR+/HER2 subtypes after the first cycle of NAC.