Consistency between 2D and 3D amide proton weighted imaging on brain tumors

Amide Proton Transfer (APT) weighted imaging is a new type of magnetic resonance molecular imaging technology derived from Chemical Exchange Saturation Transfer (CEST) technology. APT weighted imaging can be carried out with 2D and 3D acquisition mode, so called as 2D- and 3D-APT respectively. There is no relevant report on the comparison of 2D and 3D-APT imaging on brain tumors. This study intends to compare and analyze the performance of 2D- and 3D-APT imaging on brain tumors through imaging and pathological data, and recommend a better APT imaging scheme to improve the diagnosis of brain tumors.