Alterations of cortical and subcortical structures in mild cognitive impairment

In this study, we investigated alterations of cortical morphology, subcortical nuclei volume and morphology in MCI using multiple morphological analysis methods. Moreover, we explored these imaging features relationship with cognitive performances and their efficiency in classification of MCI using support vector machine (SVM). We speculate that combining volumetric and morphological analysis methods will outperform than single analysis method in MCI identification.