Relationship between Lenticulostriate Arteries Numbers and White Matter Changes in Cerebral Small Vessel Disease Patients

In this study, according to the number of lenticulostriate arteries (LSAs), cerebral small blood vessel disease (CSVD) was divided into three groups. Differences of typical CSVD markers and whole brain analysis based on diffusion tensor imaging (DTI) were explored among three groups. It was found that with the decrease of the number of LSAs, the volume of WMH and the scope and extent of fiber tract damage increased. Results show that the change of LSAs have the potential to represents extensive subcortical microvascular damage of brain tissues in CSVD.