Osteosarcoma (OSA) is the most common bone cancer in young adults and dogs and almost invariably lethal when the cancer spreads. MR-guided cryoablation offers the potential to cause direct bone necrosis and palliative pain management and has shown the potential to upregulate the immune response in prostate and breast cancer to prevent or shrink metastatic disease. The current study seeks to determine the immune response of MR-guided cryoablation in spontaneously occurring canine osteosarcoma in comparison to X-ray-guided intratumoral Stimulator of Interferon Gene (STING) immunotherapy as determine by survival time and measurement of inflammatory infilitrates.
No takes yet. Share an insight, caveat, or question.
Kraitchman et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: