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Accelerated MRI could significantly improve image quality of lung imaging without increasing costs, especially for low field strengths. The signal decay of a series of undersampled xenon-129 images is fitted to the Stretched-Exponential-Model to yield higher SNR. The proposed method was implemented in undersampled phantom images at low field (0.074T) and human lung images at high field (3T) using the FGRE pulse sequence with hyperpolarized 129Xe; SNR was significantly improved within the same scan duration compared to a fully-sampled image. Potential issues with the compressed-sensing reconstruction are identified and possible solutions presented to promote robustness of method.
Perron et al. (2024) studied this question.