Navigator-based slice tracking for liver pCASL using spin-echo EPI acquisition

Liver perfusion is an important physiological parameter in health and disease (1,2). In the measurement of liver perfusion using arterial spin labelling (ASL), respiratory motion is a major challenge. In this study, respiratory motion information is acquired from a projection signal and used to adjust the position of the excited slice in real time. The feasibility of free-breathing multi-slice liver perfusion imaging using spin-echo EPI based pseudo-continuous ASL (pCASL) with navigator-based slice tracking method is investigated.