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A previous study in the liver suggested that DWI can be used for virtual elastography. Here, we investigate the potential correlations between DWI-derived parameters and MR elastography (MRE) stiffness measurements in sixteen patients with brain cancer. The highest cross-correlation was obtained between stiffness and the shifted ADC map with b-values 1000 and 3000 s/mm² (median cross correlation 0.91). However, no correlation between mean values of MRE and sADC1000,3000 was found in normal-appearing white and gray matter, nor in tumor regions. This could be due to a too simple diffusion model and the anisotropic tissue structure of the brain.
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Svensson et al. (2024) studied this question.
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