Rapid Radiofrequency Coil Prototyping for Hyperpolarized Carbon-13 Imaging

Dynamic nuclear polarization magnetic resonance spectroscopic imaging (DNP-MRSI) of hyperpolarized carbon-13 (HP 13C) is an exciting new imaging technique that provides valuable information about the metabolism of disease states. Though there are many hyperpolarized substrates that can be used to investigate metabolism in a variety of models, the application of this technology often requires custom radiofrequency (RF) coil design. Furthermore, different coils within the same project may provide different results. In this study, we utilized 3D printing molds to generate inductors along with printed circuit board (PCB) designs to create a high reproducibility (<1% variation) pipeline for MR coils.