The alterations of glymphatic system function in left hemisphere and right hemisphere and the asymmetric features of glymphatic system were not clear in temporal lobe epilepsy (TLE) patients. We investigated the glymphatic system function in TLE patients and evaluated the asymmetric features of glymphatic system by using DTI-ALPS method. Our findings indicated leftward asymmetric tendency of glymphatic system in adult human brain. The abnormality of glymphatic system asymmetry in LTLE was also found. The glymphatic system function was impaired and more severe alterations of glymphatic system in ipsilateral hemisphere than contralateral hemisphere in TLE patients.
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Zhao et al. (2024) studied this question.
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