Vasodilator Stress Myocardial Strain in Coronary Artery Disease：An Animal Study With Histological Validation

ATP can cause a pronounced positive inotropic effect on human heart. CMR-FT even at rest provides an excellent negative predictive value for myocardial ischemia and infarction in patients with CAD. CMR-FT is easy to perform without the need for dedicated acquisition and complex post-processing which can be applied to standard CMR cine sequences. Rest myocardial strain might be a noninvasive option serving as an additional gatekeeper for CAD patients with a needle-free test. Human studies are needed to validate these findings in a multicenter setting and to test whether CMR-FT can be incorporated into clinical guidelines.