We applied a dynamic whole-brain network metric, redundancy, to a community-based middle-aged and elderly population, revealed the potential mechanisms of SVD on cognitive impairment ; we also explored the relationship between cognitive reserve and brain redundancy metric. We found that aging, hypertension and lacunes could impair redundancy in brain networks, whereas better brain redundancy corresponds to better executive function, which partly explains the potential mechanism of cognitive impairment by SVD. Secondly, we found no significant correlation between redundancy and cognitive reserve.
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Cui et al. (2024) studied this question.
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