The open-source method Prototype of Myocardial T1 mapping (ProMyoT1) created with Pulseq was tested in vivo in healthy subjects to evaluate its repeatability and compare its performance with that of the clinical MOLLI method. ProMyoT1 provided myocardium T1 values similar to those obtained with MOLLI. The precision was better for MOLLI, but the repeatability measures (Coefficient of Variation and Repeatability Coefficient) were similar in both methods. The developed ProMyoT1 method was shown to be reliable and should improve the accessibility to T1 mapping, while also enabling fast sequence prototyping so that further improvements can easily be tested.
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Gaspar et al. (2024) studied this question.
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