In this study, a novel radially-sampled echo-planar spectroscopic imaging (rEPSI) sequence was implemented at a clinical 3T MR scanner to enable the non-invasive investigation of metabolic processes via hyperpolarized 13C substrates in real-time. Customized data analysis pipelines yielded high quality spectra and volumetric intensity maps for in vivo experiments using hyperpolarized [1-13C]pyruvate. Data extracted from k-space center points enabled a non-localized quantification of T1 values.
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Awenius et al. (2024) studied this question.
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