The aim of this study is the evaluation of the influences of previously applied gadolinium-based contrast media, differing field strength and differing imaging sequence on the lately proposed perfusion quantification for PREFUL MRI. The results indicate severe alterations and distortions of the quantified perfusion parameters after gadolinium administration and depending on the field strength and on the applied sequence type. The results show, that future multicenter studies need to strictly adhere to an identical imaging protocol using the same field strengths to generate comparable results across all sites.
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Glandorf et al. (2024) studied this question.
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