Radiomic feature reliability of protein-based amide proton transfer-weighted images of brain tumors acquired with compressed sensing

Sensitivity encoding (SENSE) is a conventional practice for accelerating APTw image acquisition. To achieve an even higher acceleration, SENSE with compressed sensing (CS-SENSE) was introduced. However, its effect on the radiomic features extracted from the APTw images was yet studied. Here we extracted radiomic features from both SENSE- and CS-SENSE-APTw images and evaluated their reliability in different regions of interest (ROIs). Moreover, filters play an important part in emphasizing specific image characteristics in radiomics. The impact of filters on the radiomic features were also discussed. Our results provided a comprehensive reference for radiomic analyses where CS is implemented for acceleration.