T2*BOLD for evaluating coronary arteries with hemodynamic changes in stable multivessel coronary artery disease

This study used T2*BOLD and QFR to evaluate coronary arteries with hemodynamic changes in coronary artery disease. Fifty patients with at least 1 significant coronary artery stenosis (diameter stenosis >50%) and 21 healthy control subjects underwent coronary angiography combined with QFR measurements and CMR. The CMR protocol consisted of T2* mapping and resting perfusion, contrasted with QFR. QFR≤0.80 was considered to indicate the presence of hemodynamic obstruction. Our study revealed that T2* BOLD and QFR have good agreement in detecting hemodynamic changes of stenotic coronary arteries. T2* BOLD is superior to semiquantitative perfusion imaging in analyzing myocardial perfusion without stress.