Simplified Protocol with mSAVA for 3D Imaging of T1, T2, Extracellular Volume, Bright-Blood and Dark-Blood Late Gadolinium Enhancement

Multi-parametric SAturation recovery and Variable flip Angle (mSAVA) acquires four 3D volumes with different T1 and T2 weightings during free-breathing to simultaneously generate whole heart T1 and T2 parametric maps. We proposed a fast and simple CMR protocol using pre- and post-contrast mSAVA acquisitions to additionally generate ECV maps, and bright-blood and dark-blood LGE images. mSAVA could comprehensively assess the myocardium over the whole heart within ~6+6 min in a cohort of twenty patients.