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Comparative assessment demonstrates comparable diagnostic performance of ccLS v2.0 in small renal masses, suggesting fat suppression expands clinical applicability.
Whether T2-weighted imaging with or without fat suppression technique affects the performance of Clear Cell Likelihood Score v2.0 (ccLS v2.0) for diagnosing ccRCC in SRMs is not known. The final results showed that the tumor signal intensity between T2-weighted imaging with and without fat suppression was statistically significant (P < 0.001), but diagnostic performance and interobserver agreement of ccLS v2.0 in the diagnosis of ccRCC based on the two imaging techniques was comparable (P>0.05). Fat-suppressed T2-weighted imaging is also applicable to ccLS v2.0. This finding is helpful to expand the clinical application scope of ccLS and increase its clinical universality.
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Hao et al. (2024) studied this question.
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