Parallel Proton and Deuterium Metabolic Imaging

1H MRSI and DMI can provide crucial metabolic information to facilitate evaluations of neurological diseases. In this work, we applied interleaved 1H/2H methodology to achieve time-efficient, parallel 1H MRSI and DMI acquisition. We first describe the necessary sequence adjustments for both nuclei, including the re-optimization of the VAPOR water suppression scheme and the incorporation of a 2H equilibrium pulse. Phantoms were then used to demonstrate that high quality 1H MRSI and DMI data can be acquired in parallel. The interleaved 1H MRSI-DMI sequence is compatible with other interleaved MRI-DMI sequences and can be implemented for a complete MRI-DMI protocol.