Early detection of disease progression is of important relevance for the management of high-grade glioma (HGG) patients. Related studies showed that perfusion-weighted MR imaging (PWI) has power to detect early recurrence of glioblastoma. Inflow-based vascular space occupancy (iVASO) is a noninvasive perfusion technology that can provide absolute blood volume of precapillary arterioles (arteriolar blood volume, BVa). In this preliminary study, the potential value of BVa in detecting subclinical recurrence of HGG was investigated. The results showed that the histogram features of BVa might have the potential to detect subclinical recurrence.
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Wu et al. (2024) studied this question.
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