Robust thalamic nuclei segmentation from T1 MRI data

This work presents a methodology for thalamic nuclei segmentation from T1w MRI. Thalamus Optimized Multi-Atlas Segmentation (THOMAS), which was originally developed for white-matter nulled (WMn) MPRAGE, is adapted for standard T1 MRI by employing synthesis techniques to make the T1 images closer to WMn contrast. Robustness is tested across image contrast, MRI manufacturer, and field strength.