High spatial resolution T2 mapping via multi-shot multiple overlapping-echo detachment imaging

A multi-shot acquisition strategy is adapted to multiple overlapping-echo detachment imaging (MOLED), implementing T2 mapping with the spatial resolution of submillimeter. Compared with ssh-MOLED (ssh- for single-shot), msh-MOLED (msh- for multi-shot) are more resistant to B0 inhomogeneity, leading to quantitative results with less distortion. Besides, msh-MOLED fulfills a high acquisition efficiency. Accuracy of msh-MOLED was validated on phantoms with a 7T zoological scanner and a 3T whole-body scanner. Higher spatial resolution also alleviates partial volume effect and results in a better structure delineation of msh-MOLED, which was corroborated with in vivo experiments.