Brain tumor metabolic maps are one application of non-invasive MR Spectroscopy (MRS), although there are many other areas of patient treatment and surgery planning that would benefit from improved MRS analysis. A fast, accurate new method for MRS is used here to estimate the ratio of Choline to NAA from simulated spectra modeled on those near a brain tumor, using simple formulas for determining the FID amplitudes that relate to metabolite intensities and concentrations. No approximate numerical integration is required. The time of computation of 0.052 seconds per voxel speeds the construction of a metabolic 3D brain map.
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Dale H. Mugler (2024) studied this question.
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