Simultaneous Quantification of Relaxation and Diffusion using MR Fingerprinting with Self-Calibrated Subspace Reconstruction

We propose a self-calibrated subspace reconstruction method for multidimensional MR Fingerprinting (mdMRF) scan for simultaneous relaxation and diffusion mapping without pulsation gating. It is distortion-free, unlike EPI-based diffusion MRI. MRF images corrupted by phase errors due to bulk and physiological motions are automatically detected using an outlier detection algorithm and corrected, in order to generate artifact-free relaxation and diffusion maps.