Hypertrophic Obstructive Cardiomyopathy (HOCM) is characterized by dynamic obstruction of blood flow in the left ventricular outflow tract. 4D flow MRI can be used for comprehensive evaluation of cardiac and aortic hemodynamics by visualization of the complex spiral LVOT 3D blood flow patterns. This study used 4D flow MRI to evaluate the degree of LVOT obstruction and the flow energy loss in patients with HOCM. The results showed that spiral flow and viscous energy loss were associated with the LVOT pressure gradient, and played a role in structural remodeling of the left ventricle.
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Zhao et al. (2024) studied this question.
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