Ventricular flow analysis and its Association with cadiac function and structure of hypertrophic cardiomyopathy: 4D flow CMR study

This study aimed to investigate the potential of ventricular flow parameters derived from four‑dimensional (4D) flow cardiovascular magnetic resonance (CMR) to accurately support assessment of hypertrophic cardiomyopathy (HCM). Our results show that reduced left ventricular (LV) residual volume was associated with LV dysfunction. Higher LV retained inflow and lower delayed ejection inflow were observed in obstructive HCM patients. Flow components and kinetic energy correlated significantly with LV functional and remodelling CMR parameters. These findings suggest that 4D flow CMR may be potential method to explain the relationship between hemodynamic and pathophysiological changes in HCM.