Cholangiocarcinoma (CCA) is a primary biliary malignancy with very poor prognosis. Early diagnostic detection and effective targeted therapies remain challenging. A novel hepatic fibrosis/CCA mouse model provides an investigative platform, but in vivo tumor detection/tracking is needed. Here we trial the use of in vivo MRI with gadoxetate disodium to detect CCA tumors and to differentiate infiltrative CCA from fibrosis in these models.
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Dou et al. (2024) studied this question.
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